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Ultra-Low Field Nuclear Magnetic Resonance: A New MRI Regime

Autor Robert Kraus, Jr., Michelle Espy, Per Magnelind, Petr Volegov
en Limba Engleză Hardback – 15 mai 2014
This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRIapproaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of lowsignal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges ofimaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.
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Specificații

ISBN-13: 9780199796434
ISBN-10: 0199796432
Pagini: 264
Ilustrații: 96 illustrations
Dimensiuni: 181 x 261 x 21 mm
Greutate: 0.82 kg
Editura: Oxford University Press
Colecția OUP USA
Locul publicării:New York, United States

Notă biografică

The authors are or have recently been members of the Los Alamos "SQUID Team" that pioneered a variety of Ultra-Low Field MRI applications including ULF MRI in conjunction with MEG (magnetoencephalography) for concurrent imaging of anatomy and function in the human brain, and ULF Relaxometry used to detect dangerous substances in security screenings.