Cantitate/Preț
Produs

Next Generation Antidepressants: Moving Beyond Monoamines to Discover Novel Treatment Strategies for Mood Disorders

Editat de Chad E. Beyer, Stephen M. Stahl
en Limba Engleză Hardback – 20 mai 2010
The World Health Organization defines depression as a primary contributor to the global burden of disease and predicts it will become the second leading cause of death by 2020. The need to develop effective therapies has never been so pressing. Current antidepressant drugs have several limitations. This 2010 book looks at the future of mood-disorder research, covering the identification of new therapeutic targets, establishing new preclinical models, new medicinal chemistry opportunities, and fostering greater understanding of genetic influences. These strategies are likely to help build a better picture of the disease process, and lead to new opportunities for patient stratification and treatment. The ultimate goal for this strand of research is to develop more personalized and effective treatments for this chronic and debilitating condition. This is essential reading for all those involved in psychopharmacologic drug development, and mental health clinicians seeking a preview of discoveries soon to influence their practice.
Citește tot Restrânge

Preț: 94999 lei

Preț vechi: 99999 lei
-5%

Puncte Express: 1425

Preț estimativ în valută:
18201 19715$ 15608£

Carte tipărită la comandă

Livrare economică 06-13 mai

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9780521760584
ISBN-10: 0521760585
Pagini: 150
Ilustrații: 27 b/w illus. 10 tables
Dimensiuni: 157 x 234 x 15 mm
Greutate: 0.45 kg
Ediția:New.
Editura: Cambridge University Press
Colecția Cambridge University Press
Locul publicării:Cambridge, United Kingdom

Cuprins

Preface Chad E. Beyer; 1. Current depression landscape: a state of the field today Laurence Mignon and Stephen M. Stahl; 2. Novel therapeutic targets for treating affective disorders Eliyahu Dremencov and Thomas Cremers; 3. Developing novel animal models of depression Lotte de Groote, Malgorzata Filip and Andrew C. McCreary; 4. Translational research in mood disorders: using imaging technologies in biomarker research Jul Lea Shamy, Adam M. Brickman, Chris D. Griesemer, Anna Parachikova and Mark Day; 5. Defining depression endophenotypes Lisa H. Berghorst and Diego A. Pizzagalli; 6. Genetic and genomic studies of major depressive disorder Roy H. Perlis; 7. Medicinal chemistry challenges in the design of next generation antidepressants David P. Rotella; 8. Application of pharmacogenomics and personalized medicine for the care of depression Keh-Ming Lin, Chun-Yu Chen and Yu-Jui Yvonne Wan; Index.

Recenzii

'This is a very useful and interesting publication with a great deal of clearly summarised information on biological depression research. It gives a concise overview of likely future directions for new treatments.' The British Journal of Psychiatry

Descriere

The future of mood-disorder research: covering identification of new therapeutic targets, preclinical models, and medicinal chemistry opportunities.