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Neurodevelopmental Disorders: Comprehensive Developmental Neuroscience

John Rubenstein, Pasko Rakic Editat de Bin Chen, Kenneth Y. Kwan
en Limba Engleză Hardback – 27 mai 2020
Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms.


  • Features leading experts in various subfields as section editors and article authors
  • Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship
  • Covers disorders of the nervous system that arise through defects in neural development
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Specificații

ISBN-13: 9780128144091
ISBN-10: 0128144092
Pagini: 426
Dimensiuni: 215 x 276 x 31 mm
Editura: ELSEVIER SCIENCE

Public țintă

Neuroscience, developmental biology researchers, including stem cells, aging and diseases. Translational neuroscience researchers

Cuprins

I: NEURAL DEVELOPMENTAL DISORDERS
1. Neurocutaneous Syndromes: Neurofibromatosis and Tuberous Sclerosis
Mustafa Sahin
2. Azetidine-2-Carboxylic Acid and Other Nonprotein Amino Acids in the Pathogenesis of Neurodevelopmental Disorders
Edward Rubenstein
3. Autisms
Antonio M. Persico
4. Developmental basis of ZIKA virus induced neuropathology
Hongjun Song and Guo-li Ming
5. iPSC Models of Human Neurodevelopmental Disorders
Flora M. Vaccarino
6. Cornelia de Lange Syndrome: Insights into Neural Development from Clinical Studies and Animal Models
Anne Leighton Calof, Rosaysela Santos, Laura Groves, Chris Oliver and Arthur D. Lander
7. Fetal Alcohol Spectrum Disorder
Sandra Mooney
8. Neural Tube Defects
Lee Niswander
9. Developmental disabilities, autism and schizophrenia at a single locus: complex gene regulation and genomic instability of 15q11-q13 cause a range of neurodevelopmental disorders
Lawrence T. Reiter
10. Lissencephalies
Elliott Sherr and Bethany Johnson-Kerner
11. Rett Syndrome
Jeffrey Lorenz Neul
12. Focal Cortical Dysplasias
Christopher A. Walsh and Alissa M. D’Gama
13. White Matter Disorders
Benjamin Lawrence Lynner Clayton, Paul Tesar, Kevin Cameron Allan, Zachary Scott Nevin and Matthew Sean Elitt
14. Language Impairments
R. Holly Fitch
15. Fragile X Syndrome
Randi Hagerman
16. Microcephalies
Youngshin Lim and Jeffrey Alan Golden

Recenzii

"This relatively succinct volume successfully meets the challenge of summarizing a field as broad as developmental neuroscience. While it could not comprehensively address every disorder, the examples are well chosen and highlight advances from diverse disciplines that are leading to major improvement in our understanding of these complex and often rare conditions. There is a problematic chapter on the "autisms," but the authors do an admirable job. They describe specific syndromes, rare genetic variants, and environmental etiologies. This can help to explain endophenotypes and may point to more broad applications for understanding developmental pathways leading to new treatments." --Doody Reviews