Neonatal and Pediatric Pharmacology: Therapeutic Principles in Practice
Editat de Sumner J. Yaffe MD, Jacob V. Arandaen Limba Engleză Hardback – 12 oct 2010
Written
by
experts
at
the
forefront
of
current
research
and
clinical
practice,Neonatal
and
Pediatric
Pharmacologyprovides
evidence-based
guidelines
for
safe,
effective,
and
rational
drug
therapy
in
newborns,
children,
and
adolescents.
Coverage
includes
specific
recommendations
for
all
major
drug
classes
and
diseases,
a
detailed
section
on
drugs
and
the
newborn,
and
chapters
on
specific
treatment
settings
such
as
the
pediatric
intensive
care
unit
and
emergency
room.
Also
included
are
chapters
on
adverse
effects
and
interactions
and
state-of-the-art
discussions
on
pharmacokinetics,
pharmacodynamics,
pharmacogenetics,
pharmacogenomics,
pharmacoproteomics,
drug
development,
and
clinical
trials
in
infants
and
children.
Appendices
include
a
neonatal
formulary
and
a
pediatric
formulary.
The Fourth Edition includes updated information on drug interactions and regulatory issues. New chapters cover nutrient supplements and biotransformation of medications by the human placenta.
The Fourth Edition includes updated information on drug interactions and regulatory issues. New chapters cover nutrient supplements and biotransformation of medications by the human placenta.
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Specificații
ISBN-13: 9780781795388
ISBN-10: 0781795389
Pagini: 1072
Ilustrații: Illustrations
Dimensiuni: 213 x 276 x 42 mm
Greutate: 2.63 kg
Ediția:Fourth
Editura: LWW
Colecția Lww
ISBN-10: 0781795389
Pagini: 1072
Ilustrații: Illustrations
Dimensiuni: 213 x 276 x 42 mm
Greutate: 2.63 kg
Ediția:Fourth
Editura: LWW
Colecția Lww
Recenzii
"This
is
truly
the
gold
standard
of
pediatric
and
neonatal
pharmacology.
It
is
much
more
extensive
than
the
standard
pediatric
drug
formulary
handbooks
and
its
size
means
it
is
designed
to
be
a
reference
in
the
office
and
not
carried
in
one's
lab
coat
pocket.
However,
it
is
a
must-have
reference
for
every
pediatric
ward
and
specialty
unit
since
drug
therapy
is
so
essential
and
often
misunderstood
and
misused."
Weighted Numerical Score: 98 - 5 Stars!
Doody Enterprises, Inc. book review, February 2011
Weighted Numerical Score: 98 - 5 Stars!
Doody Enterprises, Inc. book review, February 2011
"Neonatal
and
Pediatric
Pharmacologyis
a
well-presented,
comprehensive
resource
covering
basic
pediatric
pharmacology
and
the
therapeutic
principles
that
underlie
the
use
of
medications
in
newborns
and
children.
It
will
be
a
helpful
reference
for
all
practitioners
who
care
for
children
and
invaluable
for
those
who
conduct
research
or
teach."
John L. Zeller, MD, PhD, Contributing Editor, Journal of the American Medical Association
John L. Zeller, MD, PhD, Contributing Editor, Journal of the American Medical Association
Cuprins
I:
GENERAL
PRINCIPLES"
1: Introduction and Historical Perspectives
2: Clinical Pharmacokinetics in Infants and Children
3: Drug Action and Therapy in the Infant and Child
4: Drug Metabolism and Disposition in Infants and Children
5: Pharmacogenetics, Pharmacogenomics, and Pharmacoproteomics
6: Compliance with Pediatric Medication Regimens
7: Clinical Trials Involving Children: History, Rationale, Regulatory Framework, and Technical Considerations
8: Ethics of Drug Research in Pediatric Populations
9: Therapeutic Drug Monitoring
10: Drug Formulations
II: DRUGS AND THE NEWBORN
11: Developmental Toxicology
12: Biotransformation of Medications by Human Placenta
13: Maternal Drug Intake and the Newborn
14: Principles of Neonatal Pharmacology
15: Perinatal Origins of Adult Defects in Drug Metabolism
16: Renal Function and Excretion of Drugs in the Newborn
17: The Excretion of Drugs and Chemicals in Human Milk
18: Drugs for Hyperbilirubinemia
19: Drugs and Lung Development
20: Pharmacologic Treatment of Neonatal Apnea
21: Drugs and Perinatal Brain Injury
22: Antiretroviral Pharmacology in Pregnant Women and Newborns
III: DRUGS IN SPECIAL POPULATIONS AND SETTINGS
23: Therapeutic Applications in Pediatric Intensive Care
24: Drug Therapy in the Pediatric Emergency Department
25: Drug Therapy in the Adolescent
26: Topical Medications
27: Ophthalmologic Drugs in Infants and Children
IV: SPECIFIC DRUGS
28: Sulfonamides
29: Penicillins, Cephalosporins, and Other Beta-Lactams
30: Aminoglycosides and Glycopeptides
31: Fluoroquinolones
32: Macrolides, Chloramphenicol, and Tetracyclines
33: Anthelminthic Drugs in Children
34: Antituberculosis Drugs
35: Antifungal Agents
36: Antiviral Drugs: Treatment of the Fetus and Newborn
37: Anticonvulsants
38: Psychopharmacology in Children and Adolescents
39: Antihistamine Drugs
40: Antiasthmatics
41: Antipyretics
42: Cardiovascular Drugs
43: Diuretics
44: Clinical Pharmacology of Antineoplastic Drugs
45: Immunosuppressive and Immunomodulatory Drugs
46: Analgesic Agents
47: Local Anesthetics for Infants and Children
48: Nonsteroidal Anti-inflammatory Drugs
49: Antihypertensive Agents
50: Gastrointestinal Drugs
51: Glucocorticoids
52: Insulin and Diabetes Mellitus
53: Thyroid Hormones
54: Growth Hormone
55: Hematologic Agents
56: Nutrient Supplements
57: Childhood Vaccines
V: ADVERSE DRUG EFFECTS AND INTERACTIONS
58: Epidemiology of Adverse Drug Effects
59: Mechanisms of Adverse Drug Reactions
60: Medication Errors
61: Pediatric Poisonings and Antidotes
62: Use of Herbal Products in Children: Risks and Unproven Benefits
63: Neonatal Abstinence Syndromes
64: Drug Interactions in Newborns and Children
VI: APPENDIX
65: Drug Formulary for the Newborn
66: Pediatric Drug Formulary
1: Introduction and Historical Perspectives
2: Clinical Pharmacokinetics in Infants and Children
3: Drug Action and Therapy in the Infant and Child
4: Drug Metabolism and Disposition in Infants and Children
5: Pharmacogenetics, Pharmacogenomics, and Pharmacoproteomics
6: Compliance with Pediatric Medication Regimens
7: Clinical Trials Involving Children: History, Rationale, Regulatory Framework, and Technical Considerations
8: Ethics of Drug Research in Pediatric Populations
9: Therapeutic Drug Monitoring
10: Drug Formulations
II: DRUGS AND THE NEWBORN
11: Developmental Toxicology
12: Biotransformation of Medications by Human Placenta
13: Maternal Drug Intake and the Newborn
14: Principles of Neonatal Pharmacology
15: Perinatal Origins of Adult Defects in Drug Metabolism
16: Renal Function and Excretion of Drugs in the Newborn
17: The Excretion of Drugs and Chemicals in Human Milk
18: Drugs for Hyperbilirubinemia
19: Drugs and Lung Development
20: Pharmacologic Treatment of Neonatal Apnea
21: Drugs and Perinatal Brain Injury
22: Antiretroviral Pharmacology in Pregnant Women and Newborns
III: DRUGS IN SPECIAL POPULATIONS AND SETTINGS
23: Therapeutic Applications in Pediatric Intensive Care
24: Drug Therapy in the Pediatric Emergency Department
25: Drug Therapy in the Adolescent
26: Topical Medications
27: Ophthalmologic Drugs in Infants and Children
IV: SPECIFIC DRUGS
28: Sulfonamides
29: Penicillins, Cephalosporins, and Other Beta-Lactams
30: Aminoglycosides and Glycopeptides
31: Fluoroquinolones
32: Macrolides, Chloramphenicol, and Tetracyclines
33: Anthelminthic Drugs in Children
34: Antituberculosis Drugs
35: Antifungal Agents
36: Antiviral Drugs: Treatment of the Fetus and Newborn
37: Anticonvulsants
38: Psychopharmacology in Children and Adolescents
39: Antihistamine Drugs
40: Antiasthmatics
41: Antipyretics
42: Cardiovascular Drugs
43: Diuretics
44: Clinical Pharmacology of Antineoplastic Drugs
45: Immunosuppressive and Immunomodulatory Drugs
46: Analgesic Agents
47: Local Anesthetics for Infants and Children
48: Nonsteroidal Anti-inflammatory Drugs
49: Antihypertensive Agents
50: Gastrointestinal Drugs
51: Glucocorticoids
52: Insulin and Diabetes Mellitus
53: Thyroid Hormones
54: Growth Hormone
55: Hematologic Agents
56: Nutrient Supplements
57: Childhood Vaccines
V: ADVERSE DRUG EFFECTS AND INTERACTIONS
58: Epidemiology of Adverse Drug Effects
59: Mechanisms of Adverse Drug Reactions
60: Medication Errors
61: Pediatric Poisonings and Antidotes
62: Use of Herbal Products in Children: Risks and Unproven Benefits
63: Neonatal Abstinence Syndromes
64: Drug Interactions in Newborns and Children
VI: APPENDIX
65: Drug Formulary for the Newborn
66: Pediatric Drug Formulary
Descriere
Written
by
experts
at
the
forefront
of
current
research
and
clinical
practice,Neonatal
and
Pediatric
Pharmacologyprovides
evidence-based
guidelines
for
safe,
effective,
and
rational
drug
therapy
in
newborns,
children,
and
adolescents.
Coverage
includes
specific
recommendations
for
all
major
drug
classes
and
diseases,
a
detailed
section
on
drugs
and
the
newborn,
and
chapters
on
specific
treatment
settings
such
as
the
pediatric
intensive
care
unit
and
emergency
room.
Also
included
are
chapters
on
adverse
effects
and
interactions
and
state-of-the-art
discussions
on
pharmacokinetics,
pharmacodynamics,
pharmacogenetics,
pharmacogenomics,
pharmacoproteomics,
drug
development,
and
clinical
trials
in
infants
and
children.
Appendices
include
a
neonatal
formulary
and
a
pediatric
formulary.
The Fourth Edition includes updated information on drug interactions and regulatory issues. New chapters cover nutrient supplements and biotransformation of medications by the human placenta.
The Fourth Edition includes updated information on drug interactions and regulatory issues. New chapters cover nutrient supplements and biotransformation of medications by the human placenta.