Cantitate/Preț
Produs

Molecular Diagnostics for Melanoma: Methods and Protocols: Methods in Molecular Biology, cartea 1102

Editat de Magdalena Thurin, Francesco M. Marincola
en Limba Engleză Paperback – 23 aug 2016
In Molecular Diagnostics for Melanoma: Methods and Protocols, expert researchers and clinicians in the field of melanoma provide updated information on biomarkers and assays for diagnosis, prognosis, and assays predicting response to treatment for routine testing. The focus of the volume is on biomarkers with established clinical validity rather than those on early discovery stage. With additional in-depth discussion of the molecular biology and pathology of melanoma, treatment options in adjuvant and metastatic setting, and implications of biomarker testing for clinical management of melanoma patients.
Written in the highly successful Methods in Molecular Biology series format, chapters include extensive introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Comprehensive and practical, Molecular Diagnostics for Melanoma: Methods and Protocols seeks to provide both clinicians and scientists with technical information and extensive background information on the wide ranging approaches available in the field of diagnostics of melanoma.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 96679 lei  38-45 zile
  Humana Press Inc. – 23 aug 2016 96679 lei  38-45 zile
Hardback (1) 125791 lei  38-45 zile
  Humana Press Inc. – 21 noi 2013 125791 lei  38-45 zile

Din seria Methods in Molecular Biology

Preț: 96679 lei

Preț vechi: 101767 lei
-5%

Puncte Express: 1450

Preț estimativ în valută:
18522 20063$ 15884£

Carte tipărită la comandă

Livrare economică 06-13 mai

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9781493960385
ISBN-10: 1493960385
Pagini: 735
Ilustrații: XXIII, 712 p. 110 illus., 94 illus. in color.
Dimensiuni: 178 x 254 x 37 mm
Greutate: 1.02 kg
Ediția:Softcover reprint of the original 1st ed. 2014
Editura: Humana Press Inc.
Colecția Humana
Seria Methods in Molecular Biology

Locul publicării:Totowa, NJ, United States

Cuprins

Part I. Clinical Challenges and Current Status of Treatment of Melanoma
 1. Novel Insights/translational Implication from the Emerging Biology of Melanoma         
            Antoni Ribas
 2. Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era
            Ryan J. Sullivan and Michael B. Atkins
 3. Integrating Molecular Biomarkers Into Current Clinical Management In Melanoma
            Ragini Kudchadkar, Geoffrey Gibney, and Vernon K. Sondak
 Part II. Biomarkers for Prediction of Response and Resistance to Treatment
 4. Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers
            Diwakar Davar, Ahmad A. Tarhini, Helen Gogas, and John M. Kirkwood
 5. Immunologic Monitoring of Cancer Vaccine Trials Using the ELISPOT Assay  
            Lisa H. Butterfield and Mary Jo Buffo
 6. Markers for Anti-Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma
            Michael A. Postow, Jianda Yuan, Shigehisa Kitano, Alexander M. Lesokhin, and Jedd D. Wolchok
 
7. Marker Utility for Combination Therapy
            Ester Simeone, Antonio M. Grimaldi, and Paolo A. Ascierto
8. Assaying for BRAF V600E in Tissue and Blood in Melanoma
            David J. Panka, James W. Mier, and Ryan J. Sullivan
 9. Selecting Patients for KIT Inhibition in Melanoma
            Richard D. Carvajal, Omid Hamid, and Cristina R. Antonescu
 10. Detecting Mechanisms of Acquired BRAF inhibitor Resistance in Melanoma
            Roger Lo and Hubing Shi
 11. Current Status of Diagnostic and Prognostic Markers in Melanoma      
            Danielle Levine and David E. Fisher
 12. Chromosomal Copy Number Analysis in Melanoma Diagnostics
            Jeffrey P. North, Swapna Vemula, and Boris C. Bastian
 13. Construction and Analysis of Multi-Parameter Prognostic Models for Melanoma Outcome
            Bonnie E. Gould Rothberg and David L. Rimm
 14. Immunohistochemical Diagnostic and Prognostic Markers for Melanoma
            Mehdi Nosrati and Mohammed Kashani-Sabet
 15. Lymphatic Invasion as a Prognostic Biomarker in Primary Cutaneous Melanoma
            Xiaowei Xu, Phyllis A. Gimotty, DuPont Guerry, Giorgos Karakousis, and David E. Elder
 16. Tumor Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis
            Tobias Schatton, Richard A. Scolyer, John F. Thompson, and Martin C. Mihm, Jr.
 17. Pathological Staging of Melanoma
            David E. Elder
 18. Genotyping of Human Leukocyte Antigen (HLA) Ancestral Haplotypes as Prognostic Marker in Cancer Using PCR Analysis
            Lisa Villabona, Emilia Andersson, Maddalena Marchesi, and Giuseppe V. Masucci
 19. B7-H Abnormalities in Melanoma and Clinical Relevance
            Barbara Seliger
 20. Melanoma Susceptibility Genes and Risk Assessment
            Alexander Marxuka-Alcalá, Michele Jacobs Gabree, and Hensin Tsao
 Part IV. Uveal Melanoma
 21. Clinical, Pathologic, and Imaging Features, and Biological Markers of Uveal Melanoma
            Hans E. Grossniklaus and Alia B. Rashid
 22. A Prognostic Test to Predict Risk of Metastasis in Uveal Melanoma Based on a 15-Gene Expression Profile
            J. William Harbour
 23. Molecular Karyotyping for Detection of Prognostic Markers in Fine Needle Aspirate Biopsy Samples of Uveal Melanoma
            Arupa Ganguly, Jennifer Richards-Yutz, and Kathryn G. Ewens
 Part V. Emerging Markers/Targets in Melanoma
24. ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment
            Christopher Lau, Keith J. Killian, Yardena Samuels, and Udo Rudloff
 25. Epigenetic Markers of Prognosis in Melanoma
            Luca Sigalotti, Elisabetta Fratta, Giulia Parisi, Sandra Coral, and Michele Maio
 26. Isolation of Melanoma Cell Subpopulations Using Negative Selection
            Ana Slipicevic, Rajasekharan Somasundaram, Katrin Sproesser, and Meenhard Herlyn
 27. Circulating Tumor Cells as Prognostic Biomarkers in Cutaneous Melanoma Patients
            Eiji Kiyohara, Keisuke Hata, Stella Lam, and Dave S. B. Hoon
 28. Detection of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma
            Yangyang Wang, Francesco Sabbatino, Xinhui Wang, and Soldano Ferrone
 29. Targeting Damage Associated Molecular Pattern Molecules (DAMPs) and DAMP Receptors in Melanoma
            Brian A. Boone and Michael T. Lotze
 30. The Clinical Use of PET/CT in the Evaluation of Melanoma
Khun Visith Keu and Andrei H. Iagaru
 Part VI. Emerging Technologies for Marker Validation
 31. Immune System Functional Pathway Analysis Using Single Cell Network Profiling (SCNP): A Novel Tool in Cancer Immunotherapy
            Alessandra Cesano
 32. Quantitative and Spatial Image Analysis of Tumor and Draining Lymph Nodes Using Immunohistochemistry and High Resolution Multispectral Imaging to Predict Metastasis
            Kim R.M. Blenman and Peter P. Lee
 33. COLD-PCR Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic Testing
            Elena Castellanos-Rizaldos, Coren A. Milbury, Minakshi Guha, and G. Mike Makrigiorgos
 34. Isolation of Circulating MicroRNAs from Microvesicles found in Human Plasma
            John F. Quackenbush, Pamela B. Cassidy, Lawrence M. Pfeffer, Kenneth M. Boucher, Jason E. Hawkes, Susan R. Pfeffer, Levy Kopelovich, and Sancy A. Leachman
 35. Detection of Circulating Tumor Cells by Photoacustic Flowmetry
            Ryan M. Weight and James A. Viator
 Part VII. Marker Validation Requirements for Clinical Applicability
 36. Statistical Design and Evaluation of Biomarker Studies
            Kevin K. Dobbin
 37. Tissue Resources for Clinical Use and Marker Studies in Melanoma
            Jonathan L. Curry, Michael A. Davies, Tiffany L. Calderone, Katherine Nathanson, Victor G. Prieto, and Jeffrey Gershenwald.

Recenzii

From the reviews:
“This substantive book is a compilation of focused reviews and laboratory protocols for biomarkers associated with melanoma and related targeted therapies. … This would be useful to anyone interested in melanoma, from clinicians wanting an update on promising molecular targets for melanoma treatment to researchers wanting detailed protocols for diagnostic or treatment monitoring assays. … If you are working in melanoma research or treating patients with melanoma, you will very much appreciate this book.” (Valerie L. Ng, Doody’s Book Reviews, March, 2014)

Textul de pe ultima copertă

In Molecular Diagnostics for Melanoma: Methods and Protocols, expert researchers and clinicians in the field of melanoma provide updated information on biomarkers and assays for diagnosis, prognosis, and assays predicting response to treatment for routine testing. The focus of the volume is on biomarkers with established clinical validity rather than those on early discovery stage.  With additional in-depth discussion of the molecular biology and pathology of melanoma, treatment options in adjuvant and metastatic setting, and implications of biomarker testing for clinical management of melanoma patients.
 
Written in the highly successful Methods in Molecular Biology series format, chapters include extensive introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
 
Comprehensive and practical, Molecular Diagnostics for Melanoma: Methods and Protocols seeks to provide both clinicians and scientists with technical information and extensive background information on the wide ranging approaches available in the field of diagnostics of melanoma.

Caracteristici

Seeks to provide both clinicians and scientists with technical information on a wide range of approaches available in the field
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts