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Mass Spectrometry Data Analysis in Proteomics: Methods in Molecular Biology, cartea 1007

Editat de Rune Matthiesen
en Limba Engleză Paperback – 23 aug 2016
Since the publishing of the first edition, the methodologies and instrumentation involved in the field of mass spectrometry-based proteomics has improved considerably.  Fully revised and expanded, Mass Spectrometry Data Analysis in Proteomics, Second Edition presents expert chapters on specific MS-based methods or data analysis strategies in proteomics. The volume covers data analysis topics relevant for quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards, among other topics.  Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
 
Updated and authoritative, Mass Spectrometry Data Analysis in Proteomics, Second Edition serves as a detailed guide for all researchers seeking to further our knowledge in the field of proteomics.
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Specificații

ISBN-13: 9781493959952
ISBN-10: 1493959956
Pagini: 415
Ilustrații: X, 405 p. 93 illus., 59 illus. in color.
Dimensiuni: 178 x 254 x 22 mm
Greutate: 0.72 kg
Ediția:Softcover reprint of the original 2nd ed. 2013
Editura: Humana Press Inc.
Colecția Humana
Seria Methods in Molecular Biology

Locul publicării:Totowa, NJ, United States

Cuprins

1. Introduction to Mass Spectrometry-Based Proteomics
            Rune Matthiesen and Jakob Bunkenborg
 
2. LC-MS Spectra Processing
            Rune Matthiesen
 
3. Isotopic Distributions
            Alan L. Rockwood and Magnus Palmblad
 
4. Retention Time Prediction and Protein Identification
            Alex A. Henneman and Magnus Palmblad
 
5. Algorithms for Database Dependent Search of MSMS Data
            Rune Matthiesen
 
6. Interpretation of Tandem Mass Spectra of Post-Translationally Modified Peptides
            Jakob Bunkenborg and Rune Matthiesen
 
7. Improving Peptide Identification Using Empirical Scoring Systems
            Robert J. Chalkley
 
8. Methods and Algorithms for Quantitative Proteomics by Mass Spectrometry
            Rune Matthiesen and Ana Sofia Carvalho
 
9. Computational Approaches to Selected Reaction Monitoring (SRM) Assay Design
            Conrad Bessant and Jun Fan
 
10. Feature Selection and Machine Learning with Mass Spectrometry Data
            Susmita Datta
 
11. Considerations in the Analysis of Hydrogen Exchange Mass Spectrometry Data
            Thomas E. Wales, Michael J. Eggertson, and John R. Engen
 
12. Permethylated N-Glycan Analysis with Mass Spectrometry
            Zhenxin Lin and David M. Lubman
 
13. Mass Spectrometry Methods for Studying Glycosylation in Cancer
            Hugo Osório and Celso A. Reis
 
14. Proteomics Data Exchange and Storage: The Need for Common Standards and Public Repositories
            Rafael C. Jiménez and Juan Antonio Vizcaíno
 
15. Tools for Protein Post Translational Modifications Analysis: FAK, A Case Study
            Catarina Fonseca, Paula Voabil, Ana Sofia Carvalho, and Rune Matthiesen
 
16. Proteomic Strategies to Characterize Signaling Pathways
            H.C. Harsha, Sneha M. Pinto, and Akhilesh Pandey
 
17. Simple Proteomics Data Analysis in the Object-Oriented PowerShell
            Yassene Mohammed and Magnus Palmblad

Textul de pe ultima copertă

Since the publishing of the first edition, the methodologies and instrumentation involved in the field of mass spectrometry-based proteomics has improved considerably.  Fully revised and expanded, Mass Spectrometry Data Analysis in Proteomics, Second Edition presents expert chapters on specific MS-based methods or data analysis strategies in proteomics. The volume covers data analysis topics relevant for quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards, among other topics.  Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
 
Updated and authoritative, Mass Spectrometry Data Analysis in Proteomics, Second Edition serves as a detailed guide for all researchers seeking to further our knowledge in the field of proteomics.

Caracteristici

Collects cutting-edge methods and protocols involving mass spectrometry-based proteomics and relevant data analysis
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts to ensure successful results
Includes supplementary material: sn.pub/extras